MS4A10

Across TCGA patient cohorts, MS4A10 mutation is significantly associated with the RNA expression of many other genes, with 1,076 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MS4A10-associated genes across cancer lineages are RN7SL837P, RPL23AP82, and YWHAZP7. Each is linked with MS4A10 in more than 2 cancer types. Because this analysis shows association rather than direction, both MS4A10-to-partner and partner-to-MS4A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL837P grouped by MS4A10-low versus MS4A10-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A10→partner) and Y-score (partner→MS4A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SL837P →	+0.154	+4.438	<.001	.006	3	3
SKCM	RPL23AP82 →	+0.435	+2.178	.005	.008	3	2
SKCM	YWHAZP7 →	+0.067	+1.933	<.001	.001	3	2
SKCM	SENP3-EIF4A1 →	+0.141	+1.861	.009	.007	3	2
UCEC	PSMD9 →	+0.351	+2.238	.006	.006	3	2
UCEC	SPRYD7 →	+0.365	+2.815	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,076 associations by consensus.

RN7SL837P by MS4A10 expression — LUSC

Explore this box plot interactively →