MRRF

Across TCGA patient cohorts, MRRF RNA expression is significantly associated with the protein abundance of many other proteins, with 15,132 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRRF-associated proteins across cancer lineages are FUBP3, ANP32B, and SSNA1. Each is linked with MRRF in more than 7 cancer types. Because this analysis shows association rather than direction, both MRRF-to-partner and partner-to-MRRF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRRF versus FUBP3 in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MRRF→partner) and Y-score (partner→MRRF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FUBP3 →	+0.324	+0.335	<.001	<.001	3	8
LSCC	ANP32B →	+0.435	+0.500	<.001	<.001	3	8
COAD	SSNA1 →	+0.638	+0.561	<.001	<.001	3	7
LSCC	SET →	+0.389	+0.597	<.001	<.001	3	7
OV	GOLGA1 →	+0.337	+0.591	<.001	<.001	3	7
LUAD	TRAF2 →	+0.331	+0.314	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,132 associations by consensus.

MRRF vs FUBP3 — GBM

Explore this scatter interactively →