MRPS9

Across TCGA patient cohorts, MRPS9 mutation is significantly associated with the RNA expression of many other genes, with 442 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPS9-associated genes across cancer lineages are RNU4-58P, RN7SL479P, and RN7SKP250. Each is linked with MRPS9 in more than 2 cancer types. Because this analysis shows association rather than direction, both MRPS9-to-partner and partner-to-MRPS9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-58P grouped by MRPS9-low versus MRPS9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS9→partner) and Y-score (partner→MRPS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU4-58P →	+0.367	+4.970	<.001	.005	3	3
UCEC	RN7SL479P →	+0.085	+3.351	.005	.004	3	3
UCEC	RN7SKP250 →	+0.195	+2.613	.003	.007	3	2
UCEC	SNORD114-18 →	+0.356	+2.977	.003	.003	3	2
UCEC	YBX1P9 →	+0.216	+2.123	<.001	.009	3	2
SKCM	DPPA2P2 →	+0.096	+4.215	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 442 associations by consensus.

RNU4-58P by MRPS9 expression — SKCM

Explore this box plot interactively →