MRPS7

Across TCGA pan-cancer cohorts, MRPS7 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MRPS7 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher MRPS7 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MRPS7 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

LSCC, LUAD, and CCRCC are the cancer types where MRPS7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Quartile	II,III,IV	0.945	0.561	.008	15	view →
LUAD	DFS	Median	II,III,IV	0.984	0.690	.008	13	view →
CCRCC	DFS	Median	All	0.853	0.633	.016	8	view →
PDAC	DFS	Quartile	All	0.471	0.233	.046	2	view →
HNSC	DFS	Median	All	0.977	0.908	.037	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

MRPS7–LSCC (DFS)

Open the LSCC breakdown →