MRPS7

Across TCGA patient cohorts, MRPS7 mutation is significantly associated with the RNA expression of many other genes, with 284 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPS7-associated genes across cancer lineages are RNU6-626P, DOC2B, and LINC02348. Each is linked with MRPS7 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPS7-to-partner and partner-to-MRPS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-626P grouped by MRPS7-low versus MRPS7-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS7→partner) and Y-score (partner→MRPS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-626P →	+0.305	+5.669	<.001	.003	3	1
UCEC	DOC2B →	-1.003	-2.700	.006	.006	3	1
UCEC	LINC02348 →	+0.424	+2.536	<.001	.001	3	1
UCEC	RPSAP73 →	+0.255	+2.424	<.001	.001	3	1
UCEC	WHAMMP3 →	+0.270	+3.914	<.001	<.001	3	1
UCEC	RBBP4P3 →	+0.086	+2.832	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 284 associations by consensus.

RNU6-626P by MRPS7 expression — CESC

Explore this box plot interactively →