MRPS7

Across TCGA cell cohorts, MRPS7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,493 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MRPS7-associated GO terms across cancer lineages are Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), rRNA 5'-end processing, and Mitotic DNA replication. Each is linked with MRPS7 in more than 14 cancer types. Because this analysis shows association rather than direction, both MRPS7-to-partner and partner-to-MRPS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by MRPS7-low versus MRPS7-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS7→partner) and Y-score (partner→MRPS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.143	+0.867	<.001	<.001	3	15
BLOOD_Myeloma	rRNA 5'-end processing →	+0.120	+0.882	.001	.001	3	14
PANCREAS	Mitotic DNA replication →	+0.145	+0.595	.003	<.001	3	14
BLOOD_Myeloma	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.120	+0.882	.001	.001	3	14
PANCREAS	Mitotic DNA replication checkpoint signaling →	+0.179	+0.889	<.001	<.001	3	13
SOFT_TISSUE	Double-strand break repair via break-induced replication →	+0.269	+0.711	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,493 associations by consensus.

Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by MRPS7 expression — UPPER_AERODIGESTIVE_TRACT

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