MRPS6

Across TCGA patient cohorts, MRPS6 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,245 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MRPS6-associated proteins across cancer lineages are SLC5A3_S559, SLC5A3, and ANK2. Each is linked with MRPS6 in more than 5 cancer types. Because this analysis shows association rather than direction, both MRPS6-to-partner and partner-to-MRPS6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPS6 versus SLC5A3_S559 in CCRCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS6→partner) and Y-score (partner→MRPS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SLC5A3_S559 →	+0.941	+0.964	<.001	<.001	3	6
OV	SLC5A3 →	+0.699	+0.779	<.001	<.001	3	5
GBM	ANK2 →	-0.296	-0.547	.005	<.001	3	4
BRCA	APP →	+0.420	+0.333	<.001	.004	3	4
OV	GART →	+0.306	+0.621	.007	.001	2	5
BRCA	PHPT1 →	-0.492	-0.602	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,245 associations by consensus.

MRPS6 vs SLC5A3_S559 — CCRCC

Explore this scatter interactively →