MRPS5

Across TCGA patient cohorts, MRPS5 protein abundance is significantly associated with the RNA expression of many other genes, with 17,322 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPS5-associated genes across cancer lineages are PDE1B, COLEC12, and NEXN. Each is linked with MRPS5 in more than 8 cancer types. Because this analysis shows association rather than direction, both MRPS5-to-partner and partner-to-MRPS5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPS5 versus PDE1B in BRCA, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS5→partner) and Y-score (partner→MRPS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PDE1B →	-0.580	-0.316	<.001	<.001	3	9
COAD	COLEC12 →	-0.905	-0.294	<.001	<.001	3	9
COAD	NEXN →	-1.223	-0.362	<.001	<.001	3	9
COAD	ZEB2 →	-0.730	-0.388	<.001	<.001	3	9
BRCA	MSRB3 →	-1.066	-0.310	<.001	<.001	3	9
UCEC	LINC00702 →	-0.560	-0.335	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,322 associations by consensus.

MRPS5 vs PDE1B — BRCA

Explore this scatter interactively →