MRPS36

Across TCGA patient cohorts, MRPS36 mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPS36-associated genes across cancer lineages are RN7SL763P, MIR4499, and CTBP2P3. Each is linked with MRPS36 in more than 2 cancer types. Because this analysis shows association rather than direction, both MRPS36-to-partner and partner-to-MRPS36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL763P grouped by MRPS36-low versus MRPS36-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS36→partner) and Y-score (partner→MRPS36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RN7SL763P →	+0.175	+5.187	<.001	.007	3	3
UCEC	MIR4499 →	+0.489	+4.081	<.001	.002	3	1
UCEC	CTBP2P3 →	+0.068	+4.453	<.001	<.001	3	1
BLCA	RNA5SP407 →	+0.577	+7.640	<.001	.009	3	1
BLCA	RNA5SP231 →	+0.893	+7.640	<.001	.009	3	1
BLCA	LINC02647 →	+0.294	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

RN7SL763P by MRPS36 expression — STAD

Explore this box plot interactively →