MRPS30-DT

Across TCGA pan-cancer cohorts, MRPS30-DT RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated MRPS30-DT data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher MRPS30-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated MRPS30-DT expression acts as an unfavorable survival marker, although some lineages such as BRCA and SKCM show a favorable association.

BRCA, UVM, and KICH are the cancer types where MRPS30-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	III,IV	0.956	0.849	<.001	87	view →
UVM	DFS	Quartile	III,IV	0.239	1.000	<.001	76	view →
KICH	OS	Median	All	0.648	1.000	.001	74	view →
UCEC	DFS	Quartile	II,III,IV	0.412	0.771	.001	72	view →
LIHC	DFS	Tertile	All	0.473	0.635	.001	41	view →
SKCM	OS	Median	III,IV	0.494	0.296	.001	27	view →
UCS	OS	Tertile	III,IV	0.729	0.342	.029	24	view →
HNSC	DFS	Median	All	0.265	0.412	.011	22	view →
KIRC	DFS	Quartile	IV	0.734	0.245	.013	18	view →
CESC	DFS	Tertile	All	0.776	0.895	.007	18	view →
LUSC	DFS	Median	All	0.812	0.604	.005	15	view →
ESCA	OS	Median	All	1.000	0.629	.012	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

MRPS30-DT–BRCA (OS)

Open the BRCA breakdown →