MRPS27

Across TCGA cell cohorts, MRPS27 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,905 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MRPS27-associated GO terms across cancer lineages are Purine nucleoside monophosphate biosynthetic process, Defense response to bacterium, and Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with MRPS27 in more than 15 cancer types. Because this analysis shows association rather than direction, both MRPS27-to-partner and partner-to-MRPS27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine nucleoside monophosphate biosynthetic process grouped by MRPS27-low versus MRPS27-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS27→partner) and Y-score (partner→MRPS27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Purine nucleoside monophosphate biosynthetic process →	+0.127	+0.840	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Defense response to bacterium →	-0.126	-1.061	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.154	+1.161	<.001	<.001	3	14
PANCREAS	'de novo' IMP biosynthetic process →	+0.169	+1.055	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.187	+1.256	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Mitochondrial DNA replication →	+0.129	+1.293	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,905 associations by consensus.

Purine nucleoside monophosphate biosynthetic process by MRPS27 expression — LARGE_INTESTINE

Explore this box plot interactively →