MRPS25

Across TCGA patient cohorts, MRPS25 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,714 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPS25-associated proteins across cancer lineages are TOP2B, DHX30, and KIAA1143. Each is linked with MRPS25 in more than 7 cancer types. Because this analysis shows association rather than direction, both MRPS25-to-partner and partner-to-MRPS25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPS25 versus TOP2B in HNSC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS25→partner) and Y-score (partner→MRPS25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TOP2B →	+0.372	+0.561	<.001	<.001	3	8
LSCC	DHX30 →	+0.204	+0.454	<.001	<.001	3	6
GBM	KIAA1143 →	+0.423	+0.455	<.001	<.001	3	6
LUAD	P4HB →	-0.334	-0.683	<.001	<.001	3	6
PDAC	TOP2B_S1413 →	+0.789	+0.271	<.001	<.001	3	6
GBM	HNRNPU →	+0.242	+0.273	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,714 associations by consensus.

MRPS25 vs TOP2B — HNSC

Explore this scatter interactively →