MRPS22

Across TCGA patient cohorts, MRPS22 protein abundance is significantly associated with the RNA expression of many other genes, with 16,667 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPS22-associated genes across cancer lineages are IFFO1, ATP8B4, and FYN. Each is linked with MRPS22 in more than 6 cancer types. Because this analysis shows association rather than direction, both MRPS22-to-partner and partner-to-MRPS22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPS22 versus IFFO1 in BRCA, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS22→partner) and Y-score (partner→MRPS22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IFFO1 →	-0.718	-0.330	<.001	<.001	3	7
HNSC	ATP8B4 →	-0.794	-0.348	<.001	<.001	3	7
UCEC	FYN →	-0.970	-0.284	<.001	<.001	3	7
OV	SYNE1 →	-0.839	-0.398	.001	<.001	3	7
UCEC	EMP3 →	-0.856	-0.372	<.001	<.001	3	7
UCEC	KCNMB1 →	-1.204	-0.367	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,667 associations by consensus.

MRPS22 vs IFFO1 — BRCA

Explore this scatter interactively →