MRPS21P8

Across TCGA pan-cancer cohorts, MRPS21P8 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MRPS21P8 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher MRPS21P8 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MRPS21P8 expression acts as an unfavorable survival marker, although some lineages such as GBM and LUSC show a favorable association.

LIHC, CESC, and GBM are the cancer types where MRPS21P8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.291	0.678	.010	36	view →
CESC	DFS	Tertile	II,III,IV	0.377	0.715	.003	24	view →
GBM	DFS	Tertile	All	0.573	0.242	.023	18	view →
READ	OS	Tertile	II,III,IV	0.187	0.653	.030	18	view →
SARC	DFS	Tertile	All	0.165	0.606	<.001	18	view →
LUSC	DFS	Tertile	All	0.795	0.382	.026	12	view →
OV	OS	Tertile	IV	0.497	0.728	.020	10	view →
THYM	DFS	Tertile	II,III,IV	0.145	0.873	<.001	9	view →
ESCA	DFS	Quartile	II,III,IV	0.503	0.239	.012	8	view →
LGG	OS	Tertile	All	0.991	0.887	.040	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MRPS21P8–LIHC (OS)

Open the LIHC breakdown →