MRPS21P8

Across TCGA pan-cancer cohorts, MRPS21P8 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MRPS21P8’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where MRPS21P8 RNA is repressed in tumor relative to normal tissue. In most cancer types MRPS21P8 is over-expressed in tumor, although a few such as ESCA and LUAD show the opposite, repressed pattern.

ESCA and LUAD are the cancer types where MRPS21P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MRPS21P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	Female	All	−0.376	.040	1	view →
LUAD	Female	All	−0.142	.001	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

MRPS21P8–ESCA

Open the ESCA breakdown →