MRPS18BP2

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, MRPS18BP2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MRPS18BP2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where MRPS18BP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MRPS18BP2 is over-expressed in tumor, although a few such as KIRP and THCA show the opposite, repressed pattern.

COAD, KIRP, and THCA are the cancer types where MRPS18BP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MRPS18BP2 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADAllAll+0.068.0024view →
KIRPAllIII,IV−0.018.0332view →
THCAAllAll−0.012.0391view →
KIRCAllAll+0.006.0241view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MRPS18BP2–COAD

Tumor-vs-normal expression box plot for MRPS18BP2 RNA in COAD.

Open the COAD breakdown →

Exploration