mitochondrial ribosomal protein S18A pseudogene 1Genealiases: []
Q-omics provides the consensus-scored MRPS18AP1 profile across patient tissues and cancer cell-line models. MRPS18AP1 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, MRPS18AP1 is differentially expressed in 11, with the highest sampling consensus in COAD. Additionally, MRPS18AP1 RNA expression shows 16,046 significant gene co-expression associations, with the highest sampling consensus in DLBC. Together, these results highlight KIRC, COAD, and DLBC as cancer lineages where MRPS18AP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MRPS18AP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MRPS18AP1 survival associations across molecular data types. MRPS18AP1 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MRPS18AP1 RNA expression–survival associations across cancer types. High MRPS18AP1 expression shows unfavorable associations in KIRC, but favorable associations in HNSC, SKCM, ESCA, BLCA and BRCA. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for MRPS18AP1 RNA expression.
This table summarizes MRPS18AP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for MRPS18AP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MRPS18AP1 shows lower tumor expression in KICH and higher tumor expression in COAD, BLCA, STAD, KIRC and LIHC. The COAD box plot shows higher MRPS18AP1 RNA expression in tumor versus normal tissue (log2 FC = +0.383, t-test p < 0.001).
This table shows molecular features associated with MRPS18AP1 in patient tissues and cancer cell lines. In patient samples, MRPS18AP1 shows the broadest associations at the RNA and protein expression levels, with DLBC recurring as the lineage with the largest associated feature set.
