MRPS18A

Across TCGA patient cohorts, MRPS18A mutation is significantly associated with the RNA expression of many other genes, with 205 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MRPS18A-associated genes across cancer lineages are RNA5SP319, RNA5SP42, and LINC01677. Each is linked with MRPS18A in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPS18A-to-partner and partner-to-MRPS18A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP319 grouped by MRPS18A-low versus MRPS18A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS18A→partner) and Y-score (partner→MRPS18A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNA5SP319 →	+0.463	+5.097	<.001	.008	3	2
SKCM	RNA5SP42 →	+0.477	+6.328	<.001	.001	3	2
SKCM	LINC01677 →	+0.066	+5.594	<.001	.004	3	2
SKCM	TRIM64DP →	+0.055	+6.797	<.001	<.001	3	2
UCEC	RPS29P32 →	+0.929	+3.277	<.001	.002	3	2
UCEC	PSMD14P1 →	+0.146	+2.724	.005	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 205 associations by consensus.

RNA5SP319 by MRPS18A expression — SKCM

Explore this box plot interactively →