MRPS15

Across TCGA patient cohorts, MRPS15 protein abundance is significantly associated with the RNA expression of many other genes, with 18,486 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPS15-associated genes across cancer lineages are CNRIP1, APH1B, and COLEC12. Each is linked with MRPS15 in more than 6 cancer types. Because this analysis shows association rather than direction, both MRPS15-to-partner and partner-to-MRPS15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPS15 versus CNRIP1 in BRCA, with a Pearson correlation of -0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS15→partner) and Y-score (partner→MRPS15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CNRIP1 →	-0.867	-0.364	<.001	<.001	3	7
OV	APH1B →	-0.815	-0.393	<.001	<.001	3	7
BRCA	COLEC12 →	-1.033	-0.255	<.001	<.001	3	7
OV	DDR2 →	-1.216	-0.411	.001	<.001	3	7
BRCA	ZCCHC24 →	-1.125	-0.251	<.001	<.001	3	7
BRCA	MSRB3 →	-1.177	-0.342	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,486 associations by consensus.

MRPS15 vs CNRIP1 — BRCA

Explore this scatter interactively →