MRPS15

Across TCGA cell cohorts, MRPS15 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,424 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MRPS15-associated GO terms across cancer lineages are Mitochondrial respiratory chain complex assembly, Establishment of meiotic spindle orientation, and Pseudouridine synthesis. Each is linked with MRPS15 in more than 11 cancer types. Because this analysis shows association rather than direction, both MRPS15-to-partner and partner-to-MRPS15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial respiratory chain complex assembly grouped by MRPS15-low versus MRPS15-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS15→partner) and Y-score (partner→MRPS15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Mitochondrial respiratory chain complex assembly →	+0.061	+0.646	<.001	<.001	3	12
STOMACH	Establishment of meiotic spindle orientation →	+0.178	+0.613	.002	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Pseudouridine synthesis →	+0.084	+0.704	.002	.001	3	11
BONE	Mitochondrial translation →	+0.101	+0.588	.001	.002	3	11
SKIN	Negative regulation of spindle checkpoint →	+0.089	+0.407	.002	<.001	3	11
SKIN	Negative regulation of mitotic spindle assembly checkpoint signaling →	+0.089	+0.407	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,424 associations by consensus.

Mitochondrial respiratory chain complex assembly by MRPS15 expression — BLOOD_Lymphoma

Explore this box plot interactively →