MRPS12

Across TCGA cell cohorts, MRPS12 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,672 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MRPS12-associated GO terms across cancer lineages are Inner mitochondrial membrane organization, Ribosome biogenesis, and rRNA metabolic process. Each is linked with MRPS12 in more than 14 cancer types. Because this analysis shows association rather than direction, both MRPS12-to-partner and partner-to-MRPS12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Inner mitochondrial membrane organization grouped by MRPS12-low versus MRPS12-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS12→partner) and Y-score (partner→MRPS12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Inner mitochondrial membrane organization →	+0.095	+0.811	<.001	<.001	3	15
LUNG_SCLC	Ribosome biogenesis →	+0.092	+0.636	<.001	<.001	3	15
LUNG_SCLC	rRNA metabolic process →	+0.099	+0.683	<.001	<.001	3	14
BLOOD_Myeloma	Mitochondrial ribosome assembly →	+0.099	+1.097	.002	.004	3	14
LUNG_NSCLC_LUSC	rRNA transcription →	+0.116	+0.839	.002	.002	3	14
BLOOD_Lymphoma	NADH dehydrogenase complex assembly →	+0.089	+0.810	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,672 associations by consensus.

Inner mitochondrial membrane organization by MRPS12 expression — BONE

Explore this box plot interactively →