MRPS10

Across TCGA patient cohorts, MRPS10 protein abundance is significantly associated with the RNA expression of many other genes, with 20,552 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPS10-associated genes across cancer lineages are SPATA6, APH1B, and PPFIA2. Each is linked with MRPS10 in more than 5 cancer types. Because this analysis shows association rather than direction, both MRPS10-to-partner and partner-to-MRPS10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPS10 versus SPATA6 in BRCA, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS10→partner) and Y-score (partner→MRPS10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SPATA6 →	-0.849	-0.460	<.001	<.001	3	6
OV	APH1B →	-0.950	-0.441	<.001	<.001	3	6
CCRCC	PPFIA2 →	-0.541	-0.179	<.001	.001	3	6
UCEC	RBMS3 →	-0.613	-0.292	.006	.001	3	6
UCEC	STARD9 →	-0.713	-0.297	<.001	<.001	3	6
BRCA	PIAS1 →	-0.610	-0.401	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,552 associations by consensus.

MRPS10 vs SPATA6 — BRCA

Explore this scatter interactively →