MRPS10

Across TCGA cell cohorts, MRPS10 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,596 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MRPS10-associated GO terms across cancer lineages are Ubiquitin-dependent protein catabolic process via the N-end rule pathway, 7-methylguanosine RNA capping, and 7-methylguanosine mRNA capping. Each is linked with MRPS10 in more than 9 cancer types. Because this analysis shows association rather than direction, both MRPS10-to-partner and partner-to-MRPS10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ubiquitin-dependent protein catabolic process via the N-end rule pathway grouped by MRPS10-low versus MRPS10-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS10→partner) and Y-score (partner→MRPS10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Ubiquitin-dependent protein catabolic process via the N-end rule pathway →	+0.107	+0.564	<.001	<.001	3	10
OVARY	7-methylguanosine RNA capping →	+0.078	+0.487	.001	.003	2	10
BLOOD_Lymphoma	7-methylguanosine mRNA capping →	+0.078	+0.666	.001	.006	2	10
URINARY_TRACT	Protein peptidyl-prolyl isomerization →	+0.108	+0.414	.006	.009	2	10
OESOPHAGUS	Ventricular cardiac muscle cell development →	+0.291	+0.950	<.001	<.001	3	9
CNS	Regulation of mitotic cell cycle spindle assembly checkpoint →	+0.096	+0.617	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,596 associations by consensus.

Ubiquitin-dependent protein catabolic process via the N-end rule pathway by MRPS10 expression — LUNG_SCLC

Explore this box plot interactively →