MRPL55

Across TCGA pan-cancer cohorts, MRPL55 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated MRPL55 data layer compared with 26 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MRPL55 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MRPL55 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and LUAD are the cancer types where MRPL55 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	All	1.000	0.774	.018	84	view →
PDAC	OS	Median	III,IV	0.873	0.260	<.001	35	view →
LUAD	DFS	Tertile	III,IV	0.768	0.281	.022	6	view →
LSCC	DFS	Median	II,III,IV	0.854	0.990	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

MRPL55–COAD (DFS)

Open the COAD breakdown →