MRPL55

Across TCGA pan-cancer cohorts, MRPL55 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of MRPL55’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MRPL55 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MRPL55 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRC, COAD, and LIHC are the cancer types where MRPL55 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MRPL55 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.766	<.001	12	view →
COAD	Female	All	+1.426	<.001	11	view →
LIHC	Male	II,III,IV	+1.507	<.001	9	view →
KICH	Female	II,III,IV	−1.210	<.001	8	view →
HNSC	Male	IV	+1.090	<.001	8	view →
BLCA	All	All	+0.548	<.001	8	view →
LUAD	Female	III,IV	+0.597	<.001	7	view →
BRCA	All	III,IV	+0.876	<.001	6	view →
UCEC	All	All	+0.749	<.001	6	view →
LUSC	All	II,III,IV	+0.637	<.001	6	view →
STAD	All	II,III,IV	+0.457	<.001	6	view →
CHOL	Male	All	+1.380	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

MRPL55–KIRC

Open the KIRC breakdown →