MRPL55

Across TCGA cell cohorts, MRPL55 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,164 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MRPL55-associated GO terms across cancer lineages are Regulation of translational termination, Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery, and Geranyl diphosphate metabolic process. Each is linked with MRPL55 in more than 10 cancer types. Because this analysis shows association rather than direction, both MRPL55-to-partner and partner-to-MRPL55 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translational termination grouped by MRPL55-low versus MRPL55-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL55→partner) and Y-score (partner→MRPL55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of translational termination →	+0.174	+0.938	<.001	.003	3	11
BLOOD_Lymphoma	Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.103	+0.682	<.001	<.001	3	11
BONE	Geranyl diphosphate metabolic process →	+0.110	+0.567	.001	<.001	3	9
BLOOD_Myeloma	Establishment of protein localization to endoplasmic reticulum membrane →	+0.099	+0.980	.002	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Tubulin complex assembly →	+0.099	+0.635	<.001	<.001	2	9
BREAST	Positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction →	-0.046	-0.447	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,164 associations by consensus.

Regulation of translational termination by MRPL55 expression — LUNG_NSCLC_LUSC

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