MRPL44

Across TCGA patient cohorts, MRPL44 mutation is significantly associated with the RNA expression of many other genes, with 706 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPL44-associated genes across cancer lineages are GMFBP1, COX5BP8, and RN7SL294P. Each is linked with MRPL44 in more than 2 cancer types. Because this analysis shows association rather than direction, both MRPL44-to-partner and partner-to-MRPL44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMFBP1 grouped by MRPL44-low versus MRPL44-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL44→partner) and Y-score (partner→MRPL44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GMFBP1 →	+0.246	+2.648	<.001	.002	3	3
COAD	COX5BP8 →	+0.309	+4.893	<.001	.005	3	3
BLCA	RN7SL294P →	+0.208	+5.899	<.001	.002	3	2
CESC	MIR4769 →	+0.672	+7.164	<.001	<.001	3	2
UCEC	RN7SL248P →	+0.109	+4.137	<.001	<.001	3	2
COAD	SNRPCP20 →	+0.774	+4.831	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 706 associations by consensus.

GMFBP1 by MRPL44 expression — UCEC

Explore this box plot interactively →