Across TCGA pan-cancer cohorts, MRPL42 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated MRPL42 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MRPL42 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MRPL42 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

COAD, LSCC, and CCRCC are the cancer types where MRPL42 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	1.000	0.891	.037	12	view →
LSCC	DFS	Median	II,III,IV	0.826	0.545	.019	8	view →
CCRCC	OS	Quartile	All	1.000	0.777	.004	5	view →
PDAC	OS	Median	III,IV	0.867	0.401	.010	5	view →
GBM	OS	Median	All	0.788	0.925	.024	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: MRPL42 tumor-vs-normal RNA expression · all MRPL42 data types