Across TCGA patient cohorts, MRPL42 mutation is significantly associated with the RNA expression of many other genes, with 174 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPL42-associated genes across cancer lineages are RNA5SP57, MIR6885, and RPS29P32. Each is linked with MRPL42 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL42-to-partner and partner-to-MRPL42 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL42→partner) and Y-score (partner→MRPL42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP57 →	+0.623	+6.739	<.001	<.001	3	2
UCEC	MIR6885 →	+0.332	+3.136	<.001	.007	3	1
UCEC	RPS29P32 →	+0.410	+2.792	.004	.006	3	1
UCEC	RNF166 →	+0.580	+3.343	<.001	.005	3	1
UCEC	METTL2B →	+0.439	+3.343	.006	.005	3	1
UCEC	HDAC3 →	+0.580	+3.354	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 174 associations by consensus.

Exploration

MRPL42 survival (RNA) · tumor vs normal (RNA) · all MRPL42 data types