Across TCGA cell cohorts, MRPL42 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,372 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MRPL42-associated GO terms across cancer lineages are Positive regulation of centriole replication, tRNA metabolic process, and DNA replication initiation. Each is linked with MRPL42 in more than 13 cancer types. Because this analysis shows association rather than direction, both MRPL42-to-partner and partner-to-MRPL42 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL42→partner) and Y-score (partner→MRPL42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of centriole replication →	+0.098	+0.939	<.001	<.001	3	14
BONE	tRNA metabolic process →	+0.066	+0.721	<.001	<.001	3	13
BONE	DNA replication initiation →	+0.156	+0.666	.005	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of tumor necrosis factor superfamily cytokine production →	-0.119	-0.939	<.001	.003	3	13
LIVER	RNA splicing, via endonucleolytic cleavage and ligation →	+0.085	+0.694	.007	.001	3	13
LUNG_NSCLC_LUAD	tRNA splicing, via endonucleolytic cleavage and ligation →	+0.062	+0.543	.005	.005	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,372 associations by consensus.

Exploration

MRPL42 survival (RNA) · tumor vs normal (RNA) · all MRPL42 data types