MRPL42

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MRPL42 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MRPL42-associated genes across cancer lineages are SPEM3 and FAM205A. Each is linked with MRPL42 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL42-to-partner and partner-to-MRPL42 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL42→partner) and Y-score (partner→MRPL42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINESPEM3 →+0.016+4.347<.001.00131
LARGE_INTESTINEFAM205A →+0.023+3.614<.001.00611
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration