Across TCGA patient cohorts, MRPL40 mutation is significantly associated with the RNA expression of many other genes, with 98 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPL40-associated genes across cancer lineages are RN7SL248P, RNU6-22P, and RNU6-831P. Each is linked with MRPL40 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL40-to-partner and partner-to-MRPL40 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL40→partner) and Y-score (partner→MRPL40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.111	+4.500	<.001	<.001	3	2
UCEC	RNU6-22P →	+0.413	+2.766	<.001	.007	3	2
UCEC	RNU6-831P →	+0.317	+3.901	<.001	.001	3	2
BLCA	RNA5SP35 →	+0.290	+5.106	.001	.008	3	2
SKCM	MIR4296 →	+0.583	+4.979	<.001	.009	3	1
UCEC	RN7SL453P →	+0.072	+4.470	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 98 associations by consensus.

Exploration

MRPL40 survival (RNA) · tumor vs normal (RNA) · all MRPL40 data types