MRPL37

Across TCGA pan-cancer cohorts, MRPL37 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated MRPL37 data layer compared with 23 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MRPL37 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MRPL37 expression acts as an unfavorable survival marker.

COAD and ESCA are the cancer types where MRPL37 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.100	0.670	<.001	12	view →
ESCA	OS	Median	II,III,IV	0.216	0.702	.014	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

MRPL37–COAD (OS)

Open the COAD breakdown →