MRPL34

Across TCGA cell cohorts, MRPL34 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,608 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MRPL34-associated GO terms across cancer lineages are Energy coupled proton transmembrane transport, against electrochemical gradient, Electron transport coupled proton transport, and Negative regulation of transcription initiation-coupled chromatin remodeling. Each is linked with MRPL34 in more than 13 cancer types. Because this analysis shows association rather than direction, both MRPL34-to-partner and partner-to-MRPL34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy coupled proton transmembrane transport, against electrochemical gradient grouped by MRPL34-low versus MRPL34-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL34→partner) and Y-score (partner→MRPL34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.101	+0.743	.003	.003	3	14
BONE	Electron transport coupled proton transport →	+0.101	+0.743	.003	.003	3	14
OVARY	Negative regulation of transcription initiation-coupled chromatin remodeling →	+0.154	+0.744	<.001	<.001	3	13
BONE	NADH dehydrogenase complex assembly →	+0.079	+0.587	.003	.001	3	11
BONE	Mitochondrial respiratory chain complex I assembly →	+0.079	+0.587	.003	.001	3	11
BREAST	Epidermis development →	-0.144	-0.774	.004	.005	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,608 associations by consensus.

Energy coupled proton transmembrane transport, against electrochemical gradient by MRPL34 expression — BONE

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