MRPL33

Across TCGA cell cohorts, MRPL33 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,341 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MRPL33-associated GO terms across cancer lineages are DNA replication proofreading, Cytoplasm protein quality control by the ubiquitin-proteasome system, and Protein linear polyubiquitination. Each is linked with MRPL33 in more than 9 cancer types. Because this analysis shows association rather than direction, both MRPL33-to-partner and partner-to-MRPL33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication proofreading grouped by MRPL33-low versus MRPL33-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL33→partner) and Y-score (partner→MRPL33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	DNA replication proofreading →	-0.161	-0.862	.005	.008	3	10
OESOPHAGUS	Cytoplasm protein quality control by the ubiquitin-proteasome system →	-0.162	-1.217	<.001	.005	3	9
URINARY_TRACT	Protein linear polyubiquitination →	-0.124	-1.072	<.001	<.001	2	10
BONE	Lactation →	-0.178	-1.013	<.001	<.001	3	9
BONE	Cellular response to nitrogen starvation →	+0.146	+0.766	<.001	<.001	3	8
BONE	Purkinje myocyte action potential →	-0.761	-0.641	.002	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,341 associations by consensus.

DNA replication proofreading by MRPL33 expression — OESOPHAGUS

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