Across TCGA patient cohorts, MRPL30 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPL30-associated genes across cancer lineages are SEPTIN7P4, KIR3DL1, and SEC22B2P. Each is linked with MRPL30 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL30-to-partner and partner-to-MRPL30 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL30→partner) and Y-score (partner→MRPL30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SEPTIN7P4 →	+0.125	+4.727	<.001	.003	3	2
UCEC	KIR3DL1 →	+0.367	+3.495	<.001	.008	3	1
UCEC	SEC22B2P →	+0.111	+3.474	<.001	.006	3	1
COAD	RNU6-1252P →	+0.526	+7.741	<.001	.009	3	1
COAD	MIR1263 →	+1.494	+7.741	<.001	.009	3	1
COAD	MIR1283-1 →	+0.726	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration

MRPL30 survival (RNA) · tumor vs normal (RNA) · all MRPL30 data types