Across TCGA patient cohorts, MRPL21 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,417 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPL21-associated proteins across cancer lineages are FEN1, MCM3, and MCM6. Each is linked with MRPL21 in more than 6 cancer types. Because this analysis shows association rather than direction, both MRPL21-to-partner and partner-to-MRPL21 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL21→partner) and Y-score (partner→MRPL21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FEN1 →	+0.424	+0.530	.004	.004	3	7
LSCC	MCM3 →	+0.652	+0.868	<.001	.001	3	6
LSCC	MCM6 →	+0.665	+0.922	<.001	<.001	3	6
LSCC	MCM7 →	+0.620	+0.815	<.001	<.001	3	6
HNSC	RFC2 →	+0.374	+1.187	<.001	<.001	3	6
LUAD	RRM2 →	+0.672	+0.547	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,417 associations by consensus.

Exploration

MRPL21 survival (RNA) · tumor vs normal (RNA) · all MRPL21 data types