MRPL20

Across TCGA cell cohorts, MRPL20 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,258 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MRPL20-associated GO terms across cancer lineages are DNA replication initiation, Regulation of DNA stability, and Negative regulation of DNA-templated DNA replication. Each is linked with MRPL20 in more than 13 cancer types. Because this analysis shows association rather than direction, both MRPL20-to-partner and partner-to-MRPL20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by MRPL20-low versus MRPL20-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL20→partner) and Y-score (partner→MRPL20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication initiation →	+0.212	+0.664	.001	<.001	3	14
BLOOD_Lymphoma	Regulation of DNA stability →	+0.104	+0.562	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of DNA-templated DNA replication →	+0.149	+0.719	<.001	.001	3	12
BREAST	Mitotic DNA replication checkpoint signaling →	+0.148	+0.830	<.001	<.001	3	12
BONE	DNA-templated DNA replication →	+0.152	+0.583	.004	.001	3	12
BREAST	DNA replication checkpoint signaling →	+0.145	+0.751	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,258 associations by consensus.

DNA replication initiation by MRPL20 expression — BONE

Explore this box plot interactively →