MRPL20

Across TCGA cell cohorts, MRPL20 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MRPL20-associated genes across cancer lineages are LGALS13, PLPPR4, and CCDC70. Each is linked with MRPL20 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL20-to-partner and partner-to-MRPL20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LGALS13 grouped by MRPL20-low versus MRPL20-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL20→partner) and Y-score (partner→MRPL20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LGALS13 →	+0.529	+4.384	<.001	.006	3	1
BLOOD_Leukemia	PLPPR4 →	+0.115	+3.729	.002	.009	3	1
BLOOD_Leukemia	CCDC70 →	+0.175	+4.037	<.001	.004	3	1
BLOOD_Leukemia	ETDB →	+0.045	+3.551	.001	.009	3	1
BLOOD_Leukemia	DGKK →	+0.029	+4.567	<.001	.001	3	1
BLOOD_Leukemia	OR8B2 →	+0.037	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

LGALS13 by MRPL20 expression — BLOOD_Leukemia

Explore this box plot interactively →