MRPL2

Across TCGA pan-cancer cohorts, MRPL2 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MRPL2 data layer compared with 27 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher MRPL2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated MRPL2 expression acts as an unfavorable survival marker.

CCRCC, LUAD, and HNSC are the cancer types where MRPL2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	III,IV	0.260	0.874	.005	28	view →
LUAD	DFS	Tertile	All	0.440	1.000	.028	6	view →
HNSC	DFS	Quartile	III,IV	0.708	0.951	.018	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

MRPL2–CCRCC (OS)

Open the CCRCC breakdown →