MRPL19

Across TCGA cell cohorts, MRPL19 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,049 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MRPL19-associated GO terms across cancer lineages are DNA-templated DNA replication, DNA replication initiation, and DNA replication. Each is linked with MRPL19 in more than 17 cancer types. Because this analysis shows association rather than direction, both MRPL19-to-partner and partner-to-MRPL19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication grouped by MRPL19-low versus MRPL19-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL19→partner) and Y-score (partner→MRPL19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	DNA-templated DNA replication →	+0.108	+0.632	<.001	.003	3	18
BLOOD_Myeloma	DNA replication initiation →	+0.197	+0.837	<.001	<.001	3	16
PANCREAS	DNA replication →	+0.100	+0.725	<.001	<.001	3	16
PANCREAS	Regulation of cell cycle checkpoint →	+0.091	+0.651	<.001	<.001	3	15
CNS	Chromosome segregation →	+0.073	+0.628	.001	<.001	3	15
PANCREAS	Maturation of 5.8S rRNA →	+0.130	+0.976	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,049 associations by consensus.

DNA-templated DNA replication by MRPL19 expression — BLOOD_Myeloma

Explore this box plot interactively →