MRPL18

Across TCGA patient cohorts, MRPL18 protein abundance is significantly associated with the RNA expression of many other genes, with 14,100 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPL18-associated genes across cancer lineages are NEXN, COLEC12, and TUBA1A. Each is linked with MRPL18 in more than 6 cancer types. Because this analysis shows association rather than direction, both MRPL18-to-partner and partner-to-MRPL18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPL18 versus NEXN in COAD, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL18→partner) and Y-score (partner→MRPL18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NEXN →	-1.057	-0.377	<.001	<.001	3	6
BRCA	COLEC12 →	-0.963	-0.249	<.001	<.001	3	6
OV	TUBA1A →	-0.865	-0.455	.006	.004	2	7
CCRCC	MT-CO2 →	+0.745	+0.256	<.001	<.001	3	6
LUAD	IGSF6 →	-0.675	-0.306	<.001	<.001	3	6
UCEC	STARD9 →	-0.633	-0.299	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,100 associations by consensus.

MRPL18 vs NEXN — COAD

Explore this scatter interactively →