MROH7-TTC4

Across TCGA pan-cancer cohorts, MROH7-TTC4 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated MROH7-TTC4 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MROH7-TTC4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MROH7-TTC4 expression acts as an unfavorable survival marker, although some lineages such as ACC and UCS show a favorable association.

KIRC, ACC, and UCS are the cancer types where MROH7-TTC4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	II,III,IV	0.403	0.618	<.001	66	view →
ACC	DFS	Tertile	All	0.805	0.408	<.001	60	view →
UCS	DFS	Tertile	II,III,IV	0.681	0.137	.001	42	view →
UCEC	DFS	Median	II,III,IV	0.271	0.681	.007	42	view →
KIRP	DFS	Tertile	All	1.000	0.543	<.001	40	view →
HNSC	DFS	Tertile	II,III,IV	0.776	0.646	.013	36	view →
BRCA	OS	Tertile	All	0.704	0.536	.001	32	view →
LGG	DFS	Median	All	0.296	0.464	<.001	32	view →
READ	DFS	Median	IV	0.369	0.765	.008	18	view →
KICH	DFS	Quartile	II,III,IV	0.638	1.000	.010	14	view →
LUAD	DFS	Tertile	All	0.230	0.418	.028	10	view →
STAD	OS	Tertile	III,IV	0.479	0.683	.017	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

MROH7-TTC4–KIRC (DFS)

Open the KIRC breakdown →