MROH7-TTC4

Across TCGA pan-cancer cohorts, MROH7-TTC4 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of MROH7-TTC4’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where MROH7-TTC4 RNA is repressed in tumor relative to normal tissue. In most cancer types MROH7-TTC4 is over-expressed in tumor, although a few such as BLCA and THCA show the opposite, repressed pattern.

BLCA, THCA, and COAD are the cancer types where MROH7-TTC4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MROH7-TTC4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	−0.153	<.001	11	view →
THCA	Male	III,IV	−0.252	<.001	8	view →
COAD	Male	II,III,IV	−0.065	<.001	8	view →
UCEC	All	II,III,IV	−0.087	<.001	6	view →
BRCA	Female	All	−0.021	<.001	6	view →
PAAD	All	All	+0.185	.007	4	view →
READ	Male	All	−0.100	.028	2	view →
HNSC	Female	All	+0.050	.033	2	view →
PRAD	All	All	−0.041	.004	2	view →
CHOL	All	All	+0.105	.024	1	view →
COAD	Female	IV	+0.085	.042	1	view →
KICH	Male	III,IV	−0.072	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

MROH7-TTC4–BLCA

Open the BLCA breakdown →