MRO

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MRO RNA expression is significantly associated with the protein abundance of many other proteins, with 14,145 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MRO-associated proteins across cancer lineages are CRTAP, STAB1, and MSR1. Each is linked with MRO in more than 5 cancer types. Because this analysis shows association rather than direction, both MRO-to-partner and partner-to-MRO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRO versus CRTAP in BRCA, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MRO→partner) and Y-score (partner→MRO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACRTAP →+0.554+0.487.001.00136
HNSCSTAB1 →+0.343+0.562<.001.00536
COADMSR1 →+0.608+0.376<.001<.00135
COADC1QC →+0.496+0.311<.001<.00135
COADCTHRC1 →+0.755+0.271<.001<.00135
OVEPB41L3 →+0.613+0.426<.001.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,145 associations by consensus.

MRO vs CRTAP — BRCA

Per-sample scatter of MRO vs CRTAP in BRCA (Pearson r = 0.31).

Explore this scatter interactively →

Exploration