Across TCGA patient cohorts, MRLN RNA expression is significantly associated with the go_rna of many other GO terms, with 6,418 significant associations in total. THCA shows the largest number of these associations.

The most reproducible MRLN-associated GO terms across cancer lineages are Nucleoside triphosphate biosynthetic process, ATP synthesis coupled electron transport, and Mitochondrial translation. Each is linked with MRLN in more than 12 cancer types. Because this analysis shows association rather than direction, both MRLN-to-partner and partner-to-MRLN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRLN→partner) and Y-score (partner→MRLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nucleoside triphosphate biosynthetic process →	+0.115	+0.223	<.001	<.001	3	12
STAD	ATP synthesis coupled electron transport →	+0.123	+0.186	<.001	.003	2	13
STAD	Mitochondrial translation →	+0.116	+0.229	<.001	.003	2	12
CESC	Calcium ion import into sarcoplasmic reticulum →	-0.076	-1.275	<.001	<.001	3	11
STAD	Mitochondrial gene expression →	+0.093	+0.213	<.001	<.001	2	12
STAD	Aerobic respiration →	+0.121	+0.267	<.001	<.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,418 associations by consensus.

Exploration

MRLN survival (RNA) · tumor vs normal (RNA) · all MRLN data types