MRGPRX8P

Across TCGA patient cohorts, MRGPRX8P RNA expression is significantly associated with the go_rna of many other GO terms, with 6,184 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MRGPRX8P-associated GO terms across cancer lineages are Establishment of protein localization to membrane, Sex differentiation, and Positive regulation of DNA metabolic process. Each is linked with MRGPRX8P in more than 6 cancer types. Because this analysis shows association rather than direction, both MRGPRX8P-to-partner and partner-to-MRGPRX8P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to membrane grouped by MRGPRX8P-low versus MRGPRX8P-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRGPRX8P→partner) and Y-score (partner→MRGPRX8P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Establishment of protein localization to membrane →	+0.108	+0.107	<.001	<.001	3	7
STAD	Sex differentiation →	+0.064	+0.107	<.001	<.001	3	7
STAD	Positive regulation of DNA metabolic process →	+0.106	+0.118	<.001	<.001	3	7
STAD	Protein homooligomerization →	+0.062	+0.116	<.001	<.001	3	7
STAD	Regulation of synaptic plasticity →	+0.042	+0.112	<.001	<.001	3	7
STAD	Negative regulation of protein localization →	+0.095	+0.109	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,184 associations by consensus.

Establishment of protein localization to membrane by MRGPRX8P expression — STAD

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