MRGPRX7P

Across TCGA pan-cancer cohorts, MRGPRX7P RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MRGPRX7P data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher MRGPRX7P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MRGPRX7P expression acts as an unfavorable survival marker, although some lineages such as BRCA and SARC show a favorable association.

OV, LUSC, and READ are the cancer types where MRGPRX7P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Tertile	II,III,IV	0.481	0.702	<.001	126	view →
LUSC	OS	Tertile	III,IV	0.075	0.691	<.001	87	view →
READ	OS	Tertile	III,IV	0.287	0.748	.001	36	view →
THCA	DFS	Tertile	IV	0.027	0.937	<.001	30	view →
BRCA	OS	Tertile	All	0.981	0.953	.008	29	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
SARC	OS	Tertile	All	0.749	0.466	.004	27	view →
BLCA	OS	Tertile	IV	0.200	0.597	.011	18	view →
LGG	OS	Tertile	All	0.407	0.837	.005	18	view →
LUAD	DFS	Tertile	All	0.964	0.799	.026	9	view →
LIHC	DFS	Tertile	II,III,IV	0.020	0.414	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

MRGPRX7P–OV (OS)

Open the OV breakdown →