MRGPRX4

Across TCGA cell cohorts, MRGPRX4 RNA expression is significantly associated with the go_rna of many other GO terms, with 869 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MRGPRX4-associated GO terms across cancer lineages are Synaptic vesicle recycling via endosome, Vacuole organization, and DNA conformation change. Each is linked with MRGPRX4 in more than 2 cancer types. Because this analysis shows association rather than direction, both MRGPRX4-to-partner and partner-to-MRGPRX4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Synaptic vesicle recycling via endosome grouped by MRGPRX4-low versus MRGPRX4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRGPRX4→partner) and Y-score (partner→MRGPRX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Synaptic vesicle recycling via endosome →	+0.084	+0.034	<.001	.006	3	3
SKIN	Vacuole organization →	+0.039	+1.096	.005	.001	3	3
SKIN	DNA conformation change →	+0.076	+1.387	<.001	<.001	3	3
SKIN	Clathrin-dependent endocytosis →	+0.041	+0.955	.004	<.001	3	3
SKIN	Establishment of protein localization to organelle →	+0.040	+1.145	.002	.002	3	3
SKIN	Phagosome maturation →	+0.067	+0.913	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 869 associations by consensus.

Synaptic vesicle recycling via endosome by MRGPRX4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →