MRGPRG

Across TCGA patient cohorts, MRGPRG RNA expression is significantly associated with the go_rna of many other GO terms, with 4,749 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MRGPRG-associated GO terms across cancer lineages are Maintenance of cell number, Vesicle targeting, and Amino acid metabolic process. Each is linked with MRGPRG in more than 7 cancer types. Because this analysis shows association rather than direction, both MRGPRG-to-partner and partner-to-MRGPRG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of cell number grouped by MRGPRG-low versus MRGPRG-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRGPRG→partner) and Y-score (partner→MRGPRG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Maintenance of cell number →	+0.065	+0.081	<.001	<.001	3	8
STAD	Vesicle targeting →	+0.061	+0.098	<.001	<.001	3	8
STAD	Amino acid metabolic process →	+0.043	+0.076	<.001	<.001	3	8
STAD	Microtubule-based transport →	+0.042	+0.058	<.001	<.001	3	7
STAD	Regulation of peptide transport →	+0.037	+0.093	<.001	<.001	3	7
STAD	Regulation of membrane permeability →	+0.065	+0.068	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,749 associations by consensus.

Maintenance of cell number by MRGPRG expression — STAD

Explore this box plot interactively →